Details

Standards of Mouse Model Phenotyping

1. Aufl.

von: Martin Hrabé de Angelis, Pierre Chambon, Steve Brown
160,99 €
Verlag:	Wiley-Blackwell (WB)
Format:	PDF
Veröffentl.:	03.09.2009
ISBN/EAN:	9783527608706
Sprache:	englisch
Anzahl Seiten:	358

In den Warenkorb

Als Gutschein

DRM-geschütztes eBook, Sie benötigen z.B. Adobe Digital Editions und eine Adobe ID zum Lesen.

Beschreibungen

Titelbeschreibung

This is the first book in the field of mouse genetics to provide comprehensive and standardized methods for the characterization of laboratory mice. The editor is Director of the German Mouse Clinic and member of the Project Committee of the German National Genome Research Network and provides here a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, he focuses on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner.

Inhaltsverzeichnis

Introduction Generation of mouse models PHENOTYPING AREAS Endocrinologic anomalies Metabolic analysis Neurologic disorders Immunology/Allergy Lung function Nociceptive features Eye disorders Molecular phenotyping Cardio-vascular disorders Host-pathogen interactions

Autorenportrait

Dr Hrabe de Angelis is Director if theInstitute of Experimental Genetics, in Munich, Germany and Director of the European Mouse Mutant Archive (EMMA), in Monterotondo, Italy. He is also cofounder of "INGENIUM Biopharmaceuticals AG". Processor Pierre Chambon is the director of the Institute of Genetics, Molecular and Cell Biology in Strasbourg. He has won numerous scientific prizes including the CNRS Gold Medal and the Grand Prix of the Foundation of Medical Reseach. Professor Steve Brown is Director of the Mammalian Genetics Unit of the MRC in Harwell, UK, and is a member of EMBO.

Back cover copy

This is the first book in the field of mouse genetics describing comprehensive and standardized methods for the characterization of laboratory mice. It provides a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, it is focused on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner.