Details
Plasmids for Therapy and Vaccination
1. Aufl.
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124,99 € |
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| Verlag: | Wiley-Blackwell (WB) |
| Format: | |
| Veröffentl.: | 11.07.2008 |
| ISBN/EAN: | 9783527612840 |
| Sprache: | englisch |
| Anzahl Seiten: | 307 |
DRM-geschütztes eBook, Sie benötigen z.B. Adobe Digital Editions und eine Adobe ID zum Lesen.
Beschreibungen
This is the first book specializing in plasmids and their biomedical use, including all relevant aspects of production, applications, quality, and regulations. Readers will discover clinical applications for the wide range of preventive and therapeutic applications using plasmid DNA. The book describes modified vector systems based on plasmids, as well as the potency of genomic research and vector design by informatics. Using the example of fish vaccination, the application of DNA vaccination in veterinary health care is reviewed, followed by a detailed overview of plasmid production technology on an industrial scale. Finally, the book considers regulatory and quality assurance aspects of such new drugs plus thire market potential.
The Biology of Plasmids<br /> Structures of Plasmid DNA<br /> Genetic Vaccination with Plasmid Vectors<br /> A Liposomal iNOS-Gene Therapy Approach to Prevent Neointimal Lesion Formation in Procine Femoral Arteries<br /> Immunotherapy of Chronic Hepatitis B by pCMV-S2S DNA Vaccine<br /> pSG.MEPfTRAP- A First Generation Malaria DNA Vaccine Vector<br /> Polyvalent Vectors for Coexpression of Multiple Genes<br /> Form Follows Function: The Design of Minimalistic Immunogenically Defined Gene Expression Constructs<br /> Synthetic Genes for Prevention and Therapy: Implications on Safety and Efficacy of DNA Vaccines and Lentiviral Vectors<br /> Plasmids in Fish Vaccination<br /> From Research Data to Clinical Trials with Plasmid DNA<br /> Plasmid Manufacturing -<br /> An Overview<br /> Quality Control of pDNA<br /> From Research Data to Clinical Trials<br /> Market Potential for DNA Therapeutics
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