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Characterization, Properties and Applications


Characterization, Properties and Applications


2. Aufl.

von: Tracey Rouault, Francesco Bonomi, Toshiko Ichiye, Michael Hendrich, Paul Lindahl, Mrinmoy Chakrabarti, Markus Ribbe, Yilin Hu, Oliver Einsle, Joe Jarrett, Russ Hille, Squire Booker, Yvain Nicolet, Juan Fontecilla, Yisong Guo, Li Jikun, Noodleman Louis, Nick Le Brun, Susana L.A. Andrade, Jason Crack, Erin Dodd, Han Wenge, Nicholas D. Lanz, Doros T. Petasis, Thomas Spatzal, Andrew Thomson

129,95 €

Verlag: De Gruyter
Format: EPUB
Veröffentl.: 21.08.2017
ISBN/EAN: 9783110478556
Sprache: englisch
Anzahl Seiten: 462

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Beschreibungen

<p>This volume on iron-sulfur proteins includes chapters that describe the initial discovery of iron-sulfur proteins in the 1960s to elucidation of the roles of iron sulfur clusters as prosthetic groups of enzymes, such as the citric acid cycle enzyme, aconitase, and numerous other proteins, ranging from nitrogenase to DNA repair proteins. The capacity of iron sulfur clusters to accept and delocalize single electrons is explained by basic chemical principles, which illustrate why iron sulfur proteins are uniquely suitable for electron transport and other activities. Techniques used for detection and stabilization of iron-sulfur clusters, including EPR and Mossbauer spectroscopies, are discussed because they are important for characterizing unrecognized and elusive iron sulfur proteins. Recent insights into how nitrogenase works have arisen from multiple advances, described here, including studies of high-resolution crystal structures. </p>
<p><strong>Tracey Rouault,</strong> NIH Bethesda, Maryland, USA </p>

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