Details
Cell Junctions
Adhesion, Development and Disease1. Aufl.
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117,99 € |
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| Verlag: | Wiley-Blackwell (WB) |
| Format: | |
| Veröffentl.: | 08.08.2008 |
| ISBN/EAN: | 9783527622108 |
| Sprache: | englisch |
| Anzahl Seiten: | 318 |
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Beschreibungen
This long-awaited, first comprehensive book on this topic of fundamental importance in our understanding of cancer begins with an overview of cellular junctions, before covering cell-matrix junctions, cell-cell junctions and cell-matrix and cell-cell adhesion in separate sections.<br> Of high interest to cell and molecular biologists, cancer researchers, oncologists, biochemists, pharmaceutists and those working in the pharmaceutical industry.
Overview of Cellular Junctions<br /> <br /> CELL-MATRIX JUNCTIONS<br /> Integrin Transmembrane Signaling<br /> Focal Adhesion<br /> Signaling Through FAK<br /> Focal Adhesion Dynamics<br /> Integrin Trafficking<br /> Hemidesmosomes<br /> Cell Matrix Adhesion in 3 Dimensions<br /> <br /> CELL-CELL JUNCTIONS<br /> Epithelial Adherens Junctions<br /> Endothelial Adherens Junctions<br /> Gap Junctions<br /> Tight Junctions<br /> Desmosomes<br /> Junctions Dynamics and Adhesion Receptor Trafficking<br /> <br /> CELL-MATRIX AND CELL-CELL CROSSTALK<br /> Adhesion Receptors in Mechanotransduction<br /> Crosstalk Between Cell-Cell and Cell-Matrix Adhesion<br /> <br />
?This volume presents an excellent overview into the world of cell adhesion. It provides important details about the main players in all aspects of cell junctions.?( <i>The Quarterly Review of Biology</i> , September 2009) <p>"This is a welcome addition to the literature that will be valued by all students of cell adhesion and morphogenesis." (<i>Doody's</i>, January 2009)</p>
Susan LaFlamme is a professor in the Center for Cell Biology and Cancer Research at the Albany Medical College in Albany NY. She obtained her B.A. from Barnard College and her PhD from Columbia University in New York NY, USA. Professor LaFlamme has received many grants for her studies on integrin signaling and has published extensively in this area. She has served on review panels for the National Institutes of Health, the American Cancer Society and the American Heart Association.<br /> <br /> Andrew Kowalczyk is an Associate Professor for Cell Biology and Dermatology at Emory School of Medicine in Atlanta GA, USA. Dr. Kowalczyk obtained his PhD at Albany Medical School in Albany NY and carried out postdoctoral studies at Northwestern University Medical School in Chicago IL, USA. He has received numerous grants and awards and has published extensively in the area of cell adhesion. He has served on review panels for the National Institutes of Health and the American Heart Association, and on several advisory committees for the Society for Investigative Dermatology.<br />
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