Details

Autophagy in Immunity and Infection


Autophagy in Immunity and Infection

A Novel Immune Effector
1. Aufl.

von: Vojo Deretic

138,99 €

Verlag: Wiley-Blackwell (WB)
Format: PDF
Veröffentl.: 21.08.2006
ISBN/EAN: 9783527608546
Sprache: englisch
Anzahl Seiten: 286

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Beschreibungen

This first book to cover this new topic at the interface of cell biology, immunology and infection biology offers a unique insight as to how the innate and possibly the adaptive immune system are shaped by cellular mechanisms. Following a comprehensive introduction to autophagy, the work features cellular mechanisms and medical implications, structured according to all major pathogens, while also covering emerging infectious diseases, such as tuberculosis. Edited by one of the authors of a groundbreaking paper on this topic.
INTRODUCTION TO AUTOPHAGY <br /> Overview of Autophagy<br /> Cell Biology and Biochemistry of Autophagy<br /> Transgenic Models of Autophagy<br /> Autophagy in Disease and Aging<br /> The Dual Roles for Autophagy in Cell Death and Survival<br /> AUTOPHAGY AND BACTERIA<br /> Autophagy and Mycobacterium Tuberculosis<br /> Autophagy Eliminates Group A Streptococcus Invading Host Cells<br /> Shigella Invasion of Host Cells and Escape from Autophagy<br /> Listeria Monocytogenes: a Model System for Studying Autophagy<br /> Coxiella Burnetii Hijacks the Autophagy Pathway to Survive<br /> Utilization of Endoplasmic Reticulum Membranes to Establish a Vacuole that Supports Replication of Legionella Pneumophila<br /> AUTOPHAGY AND VIRUSES<br /> Endogenous MHC Class II Antigen Processing of Viral Antigens<br /> Autophagy in Antiviral Host Defense
Vojo Deretic is full professor and vice-chair at the Department of Molecular Genetics and Microbiology of the University of New Mexico Health Sciences Center. From 1997 to 1999 he was Foundation Lecturer of the American Society for Microbiology. He published one of the groundbreaking papers on this topic in CELL.
The first book to cover this new topic at the interface of cell biology, immunology and infection biology offers a unique insight as to how the innate and possibly the adaptive immune system are shaped by cellular mechanisms. Following a comprehensive introduction to autophagy, the work features cellular mechanisms and medical implications, structured according to all major pathogens, while also covering emerging infectious diseases, such as tuberculosis. Edited by one of the authors of a ground-breaking paper on this topic.

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